Treffer: Automatic registration of breast cancer tissue
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This Masters thesis explores the development of a Python application designed to perform registration and overlap of breast cancer histopathological images with different stains, such as HE, HER2, PR, KI67, and ER. The application features three main functionalities: register, transfer, and crop. The register function performs rigid and non-rigid registration, storing results in a user-specified path. The transfer function registers images and transfers medical annotations between them. The crop function optimizes computational efficiency and ensures accurate registration by working on cropped sections of images. This project leverages the VALIS (Virtual Alignment of Pathology Image Series) framework and integrates multiple tools to handle various image formats and perform precise alignment tasks.